Functional Characterization of New Mutations in Wilson Disease Gene (ATP7B) Using The Yeast Model. Şimşek Papur, Ö., Terzioglu O., Koç A., J of Trace El. in Med. and Biol. (2015) In Press
Kaya A, Lobanov AV, Gerashchenko MV, Koren A, Fomenko DE, Koc A, Gladyshev VN. Thiol Peroxidase Deficiency Leads to Increased Mutational Load and Decreased Fitness in Saccharomyces cerevisiae. Genetics. 2014 Aug 29. pii: genetics.114.169243
A. E. Atik, G. O. Bozdağ, E.Akıncı, A. Kaya, A. Koç, T. Yalçın, H. Ç. Karakaya, “Proteomic changes during boron tolerance in barley (Hordeum vulgare) and the role of vacuolar proton-translocating ATPase subunit E”, Turkish Journal of Botany (ISI) , 2011 , DOI: 10.3906/bot-1007-29
Hacioglu, E., Esmer, I., Fomenko, DE., Gladyshev VN., and Koc, A. The roles of thiol oxidoreductases in yeast replicative aging. Mech. Of Aging and Dev., 131(11-12):692-9, 2010.
Kaya, A., Koc, A., Lee, BC., Fomenko, DE., Rederstorff, M., Krol, A., Gladyshev, VN. Compartmentalization and Regulation of Mitochondrial Function by Methionine Sulfoxide Reductases inYeast. Biochemistry, 49(39), 8618–8625, 2010.
Demir AB, Koc A. Assessment of chronologicallifespan dependent molecular damages in yeast lacking mitochondrial antioxidantgenes. Biochem Biophys Res Commun. Sep 10;400(1):106-10. 2010.
Stoner CS, Pearson GD, Koç A, Merwin JR, Lopez NI, Merrill GF. Effect of Thioredoxin Deletion and p53 Cysteine Replacement on Human p53 Activity in Wild-type and Thioredoxin Reductase Null Yeast. Biochemistry, 48 (38), 9156–9169, 2009
Kaya, A., Karakaya, CH., Fomenko, DE., Gladyshev, VN., Koc, A. Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast. Mol Cell Biol. Jul;29(13):3665-74, 2009.
Le DT, Lee BC, Marino SM, Zhang Y, FomenkoDE, Kaya A, Hacioglu E, Kwak GH, Koc A, Kim HY, Gladyshev VN. Functional analysis of free methionine-R-sulfoxide reductase from Saccharomycescerevisiae. J Biol Chem. Feb 13;284(7):4354-64. 2009.
Fomenko DE, Novoselov SV, Natarajan SK, Lee BC, Koc A, Carlson BA, Lee TH, KimHY, Hatfield DL, Gladyshev VN. MsrB1(methionine-R-sulfoxide reductase 1) knock-out mice: roles of MsrB1 in redoxregulation and identification of a novel selenoprotein form. J Biol Chem. Feb 27;284(9):5986-93. 2009.
Unlu ES, Koc A. Effectsof deleting mitochondrial antioxidant genes on life span. Ann N Y Acad Sci. Apr;1100:505-9. 2007.
Koc A, Gladyshev VN. Methioninesulfoxide reduction and the aging process. Ann N Y Acad Sci. Apr;1100:383-6. 2007.
Koc A, Merrill GF. Checkpointdeficient rad53-11 yeast cannot accumulate dNTPs in response to DNAdamage. Biochem Biophys Res Commun. Feb 9;353(2):527-30. 2007.
Koc A, Mathews CK, Wheeler LJ, Gross MK, MerrillGF. Thioredoxinis required for deoxyribonucleotide pool maintenance during S phase. J Biol Chem. Jun 2;281(22):15058-63. 2006.
A. Koç, H.C. Karakya, E.S. Ünlü, “Evidence for the presence of a second electron donor for cytoplasmic thioredoxins in the yeast S. cerevisiae.”, Turkish Journal Biology , 133-138 pp., 2006. Puan:10
Koc A, Gasch AP, Rutherford JC, Kim HY, Gladyshev VN. Methioninesulfoxide reductase regulation of yeast lifespan reveals reactive oxygenspecies-dependent and –independent components of aging. Proc Natl Acad Sci U S A. May 25;101(21):7999-8004. 2004.
Koç A, Wheeler LJ, Mathews CK, Merrill GF. Hydroxyurea arrests DNA replication by a mechanism that preserves basal dNTP pools. J Biol Chem. Jan 2;279(1):223-30. 2004.
Koç A, Wheeler LJ, Mathews CK, Merrill GF. Replication-independent MCB gene induction and deoxyribonucleotide accumulation at G1/S in Saccharomycescerevisiae. J Biol Chem. Jan2;279(1):223-30. 2004.
Kumar RA, Koc A, Cerny RL, Gladyshev VN. Reactionmechanism, evolutionary analysis, and role of zinc in Drosophilamethionine-R-sulfoxide reductase. J Biol Chem. Oct 4;277(40):37527-35. 2002.
Kryukov GV, Kumar RA, Koc A, Sun Z, Gladyshev VN, SelenoproteinR is a zinc-containing stereo-specific methionine sulfoxidereductase. Proc Natl Acad Sci U S A. Apr 2;99(7):4245-50. 2002.